《大汉巾帼》是由李平执导，蒋勤勤,聂远,王辉主演的国产剧。该电视剧于2005年在大陆上映。秦末汉初，楚汉战争悲惨壮烈，在战火中身受重伤的刘邦大将利苍，无意中闯入云梦泽畔的风镇。利苍的到来，改变了这村里几个青年男女一生的命运。少女辛追救回了伤重晕倒的利苍，被临终的老父托付给利苍，少女一夕之间变成将军夫人；邻家小子符申追随守护辛追，从此做了江湖侠客；妓女南施被刘邦看中，从此沉沦于追名逐利。 符申、利苍、刘邦一个个男人拜倒在辛追的石榴裙下，南施妒火中烧，立誓有朝一日定要把辛追踩在脚下。她凭借自己的美艳姿色，把男人当作扶梯，爬上长沙王夫人的位置。她将利苍毒死在战场上；她把辛追新婚不久的儿子困死于空城之中；她挑拨符申与辛追之间原本就负担太重的情丝，令他们在绝望中彼此伤害。阴谋并没有就此结束，南施的怨毒，宫庭的血腥，战争的残酷，江湖的险恶，把辛追这个孤独的女人逼进血雨腥风的噩梦……
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