《大国医》是由吴子牛执导，赵文瑄,徐帆,王绘春主演的国产剧。该电视剧于2009年在大陆上映。郭氏平乐正骨已有二百余年行医史，清代时医过慈禧太后，德高医精，闻名遐迩。郭家一直人丁不旺，到第四代传人郭一山，娶了两房夫人都相继去世，只留下一个小女儿。为传宗接代，让郭氏正骨代代相传，郭一山又急急迎娶小他十一岁的山村姑娘云鹤鸣。迎亲路上，突然有人抬着担架拦住了迎亲队伍，原来是意大利传教士马利奇大腿受伤，急切赶来，拦路求医。虽然民间讲究迎亲队伍不能中途停止，否则，往后的日子会风波不断，但郭一山还是下马救人。未想到马利奇曾与山中土匪结怨，结婚喜宴上，土匪大闹喜宴，并绑架了郭一山。原来是村中“永春堂”堂主刘仙堂悄悄向土匪告密，欲置郭一山于死地。此时除了新娶来的媳妇外，郭家只有病弱的老父、花娘和一个四岁幼女，无人能为之奔走相救。新媳妇还在新房顶着盖头，得知事情原委，毅然决定，女扮男装，与和事佬孙大头一起……
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