《惊心动魄之毁尸灭迹》是由王珈,沈东执导,李幼斌,涓子,刘金山,刘之冰主演的恐怖片。该电影于2003年在大陆上映。影片为“非典”题材,故事发生在一列封闭的火车上,通过各色人等的突出表现逼真的反映了“非典’来临时人们那种由恐慌到无奈的接受,再到鼓起勇气战胜“非典”的心态转变,是以真实事件为基础,被人称为“中国最为真实的灾难电影”。2003年春,一种严重的传染病肆虐全国,某市一名疑似病人突然失踪,为防止疫情扩散,省长指示一定要切断传染源。女军医杨萍(涓子饰)临危受命,离开手术室正在抢救中的母亲,登上1120次列车,急赴求援工作。恰巧,那位失踪的疑似病人就在这班列车中。杨萍获知后挺身而出,在列车长(沈慧芬饰)和乘警长(李幼斌饰)的全力帮助下,迅速展开了一场查找疑似病人的特殊战斗。很快,终于找到疑似病人并把他送下火车。列车继续前进,危机似乎解除,但在杨萍未及喘息之际,却发现发烧病人迅速增多,疫情已经在车厢内蔓延,更为致命的是,乘客深陷恐慌之中,强烈要求下车。然而,为防止疫情向农村和山区扩散,省委和铁道部决定途中不再停车,医疗物资的匮乏、乘客的恐慌以及重症患者危在旦夕……为拯救整车乘客的生命,杨萍的昔日恋人,呼吸科专家梁文勇(刘之冰饰)冒着生命危险,乘直升飞机空降到时速150公里的列车上,与杨萍并肩战斗。
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