血意少年全集主要以魔界为舞台，主角斯塔滋是魔界东部地区的老大之一，作为吸血鬼的他并没有觉得拥有傲慢贵族气质以及吸血人类之血是什么大不了的事情，所以他不会去吸人血。除此之外，他自己十分喜欢并敬仰日本的文化，房间里有不少日本动画、漫画及游戏的收藏。有一天他的手下碰到了不知为何会出现在魔界的人类女孩柳冬实，命令手下把人带来的他在这段空隙的时间内，忙着打扮、准备着如何打招呼等等，明显这让他十分期待，双方见到后聊着游戏之类的话题。另一边他的手下遇到了侵略者，之后斯塔滋到了现场帅气地击退了侵略者，在回到房间时发现那个女孩已被植物怪兽吞噬只剩下了骨头，而她也化作了幽灵。虽然对失去魅力的幽灵冬实感到失望，但斯塔滋下定决心要让她复活，故事也就这样展开了。
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