该片以5.12大地震为背景，叙述地震后从汶川随救援队来到成都临时安置中心的小女孩轩轩，在成都丢失了爸爸送给他的心爱毛绒玩具——酷巴熊。此时爸爸妈妈都还没有生还的消息。轩轩把所有的情感和希望寄托到了爸爸送的礼物——酷巴熊上。轩轩通过自己的努力和坚持克服了种种困难，在得到政府、社会、媒体和众多好心人的帮助下找回酷巴熊的感人故事。 影片全部镜头均取自成都，众多来自灾区的群众将本色参演。影片主角由可爱的小演员任婉涵饰演，她曾与周华健、午马、莫文蔚等港台一线明星同台合作，目前正在实地体验生活。影片另以主角则是动漫形象“酷巴熊”，该形象是一只胖嘟嘟、憨态可爱的3D大熊猫造型，但他拥有河马一样宽大的脸庞以及奶牛似地花斑，在目前所有的卡通大熊猫世界里完全是个另类。更新颖的是，片中这个小家伙将会表演中国功夫及众多巴蜀绝技，如变脸、吐火、顶碗等川剧绝活。
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