《怪奇大作战 神秘档案》是由鹤田法男,绪方明,棚田由纪,田口清隆执导，上川隆也,原田泰造,田畑智子,村井良大,高桥真唯,原田美枝子主演的日韩剧。该电视剧于2013年在日本上映。为了应对日新月异的高科技犯罪，独立于司法和警察系统之外的第三方机构特殊科学搜查研究所（SRI）宣布成立。在所长的矢千景（原田美枝子饰）的主持下，牧史郎（上川隆也饰）、三泽京助（原田泰造饰）、小川纱织（高桥真唯饰）、野村洋（村井良大饰）等四名成员一次次奔赴各种离奇诡异的犯罪现场。《血球》森林中惊现全身脱水的干尸，死者生前曾被血球追杀；《伏地女王》一男子被突然出现的蚂蚁咬成白骨，这一切似乎与某个全女性组成的生化公司有关；《在黑暗中蠢蠢欲动的美少女》多年前死去的七岁童星，突然出现在夜晚的街头，她一边唱歌一边将靠近她的人化作液体；《窥视深渊之人》接连数起设计巧妙的高智商高科技犯罪，矛头却直指牧史郎。
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